Research Scientist in Biochemistry and Molecular Genetics - Weaver Lab

The Weaver Lab in the Department of Biochemistry and Molecular Genetics at the University of Virginia School of Medicine is seeking a creative and highly motivated Research Scientist to significantly contribute to our labs goal of identifying mechanisms of DNA repair in chromatin.

The Weaver Lab is dedicated to unraveling mechanisms of DNA repair in chromatin and harnessing these mechanistic insights to improve human health. Current research projects in the lab aim to: (1) Determine how DNA damage impacts chromatin structure, stability, and dynamics; (2) Determine how DNA repair enzymes identify and process DNA damage in chromatin; and (3) Determine how chromatin-modifying enzymes regulate chromatin structure to facilitate DNA repair. The lab addresses these research aims using a powerful combination of biochemistry, single-molecule fluorescence microscopy, structural biology, and cellular biology approaches. The Research Scientist will lead their own independent research project related to one of the three overarching aims of the Weaver Lab.

MINIMUM REQUIREMENTS:

Education: Requires a doctoral degree or master's degree with significant experience.

Experience: None

Licensure: None

Preferred Requirements:

• Candidates should possess a doctoral degree in Biochemistry, Molecular Biology, Structural Biology, or a related Biomedical Sciences field at the time of hiring.

• Candidates should also possess an additional 3 years of research experience in a relevant research setting (e.g. Postdoctoral Associate).

• Strong track-record of scholarly publications.

Preferred Skills

Prior research experience in chromatin biology and/or DNA damage repair is advantageous. Prior experience in two or more of the following techniques is highly preferred:

• Protein and/or nucleic acid biochemistry (e.g. nucleic acid purification, protein expression and purification, or in vitro reconstitution experiments)

• Structural biology techniques (e.g. cryo-EM, X-ray crystallography, or NMR)

• Single-molecule fluorescence techniques

• Cell biology approaches (e.g. CRISPR-Cas9 gene editing, fluorescence microscopy, or NGS methodologies)

The University will perform background checks on all new hires prior to employment. A completed pre-employment health screen is required for this position prior to employment.

To Apply:

Please apply through the UVA job board, and search for R0068851.

Internal applicants must apply through their UVA Workday profile by searching 'Find Jobs' and search for R0068851.

Complete an application online with the following documents:

• CV

• Cover letter

Upload all materials into the resume submission field, multiple documents can be submitted into this one field. Alternatively, merge all documents into one PDF for submission. Applications that do not contain all required documents will not receive full consideration.

References will be completed via UVA's standardized process Skill Survey. A total of five references will be requested via Skill Survey during the final phase of the interview process.

For questions regarding this position, please contact Dr. Tyler Weaver, Assistant Professor, Department of Biochemistry and Molecular Genetics.

For questions about the application process, please contact Michelle Johnson, Recruiter.

For more information about UVA and the Charlottesville community please see http://www.virginia.edu/life/charlottesville and https://embarkcva.com/.

The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex, pregnancy, sexual orientation, veteran or military status, and family medical or genetic information.