Junior, Assistant, Associate, or Full Specialist - Dumesic Lab

Junior, Assistant, Associate, or Full Specialist - Dumesic Lab

The Dumesic Lab (www.dumesiclab.org) at the UCSF Diabetes Center is seeking applicants for a full-time Specialist position at the Junior, Assistant, Associate, or Full rank. Our lab studies energy metabolism-the means by which cells transform and utilize chemical energy-and how disturbances in this process bring about metabolic diseases such as obesity, diabetes, and cachexia. We seek to understand what gives rise to metabolic disease and why these conditions cause so many problems throughout the body. We believe that investigation of basic gene regulatory mechanisms can help explain the logic behind these complex pathophysiological connections-and provide new avenues for therapy. Toward this goal, we seek genes responsible for the specialized metabolic programs carried out by fat and muscle cells. We then examine the mechanisms by which these genes are activated and carry out their functions, with the hope of discerning the signals that initiate and propagate tissue dysfunction during metabolic disease.

We are a new lab creating a collaborative environment of ambitious, interdisciplinary science that leverages genetics, biochemistry, mouse physiology, and bioinformatics to discover new biology and inspire novel therapy for disease. Candidates will be expected to contribute to research projects in the lab through work on molecular cloning, tissue culture, CRISPR-mediated gene editing, and protein purification, as well as through isolation and analysis of DNA, RNA, and protein from cells and tissues. An essential component of the work will involve mice: weaning, genotyping, and mouse colony management, as well as metabolic experiments such as high-fat diet feeding and glucose tolerance testing. Specialists will be paired with senior scientists for training in these techniques, and exceptional Specialists will over time take on responsibility for designing their own experiments, developing new ideas, presenting at lab meetings, and participating in the writing of grants and papers. Importantly, the Specialist will be expected to assist with managing day-to-day lab operations and purchasing, as well as in performing some general lab duties.

Required Qualifications:

• Junior Specialist - Baccalaureate degree (or equivalent degree) or at least four years of research experience.
• Assistant Specialist - Master's degree or a baccalaureate degree with three or more years of research experience.
• Associate Specialist - Master's degree (or equivalent degree) or five to ten years of relevant experience.
• Full Specialist - terminal degree (or equivalent degree) or ten or more years of relevant experience.
• Candidates must meet the required qualifications at the time of appointment.
• Applicants' materials must list current and/or pending qualifications upon submission.

We are seeking at least a 2-year commitment. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available. Furthermore, the world-renowned UCSF environment-in which cutting-edge ideas and technologies in the basic sciences contribute to advances in human medicine-is an ideal setting to work toward long-term career goals in biomedicine. Candidates will receive opportunities for training in oral and written communication, advising on graduate/medical school applications, and numerous opportunities for networking with peers and with other scientists.

See Table 24B for the salary range for this position. A reasonable estimate for this position is $53,100 - $188,200.

Please apply online at https://aprecruit.ucsf.edu/JPF05442.

• 3 required (contact information only)

As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

As a condition of employment, the finalist will be required to disclose if they are subject to any final administrative or judicial decisions within the last seven years determining that they committed any misconduct, are currently being investigated for misconduct, left a position during an investigation for alleged misconduct, or have filed an appeal with a previous employer.

* "Misconduct" means any violation of the policies or laws governing conduct at the applicant's previous place of employment, including, but not limited to, violations of policies or laws prohibiting sexual harassment, sexual assault, or other forms of harassment, discrimination, dishonesty, or unethical conduct, as defined by the employer.

* UC Sexual Violence and Sexual Harassment Policy: https://policy.ucop.edu/doc/4000385/SVSH

* UC Anti-Discrimination Policy for Employees, Students and Third Parties: https://policy.ucop.edu/doc/1001004/Anti-Discrimination

* APM - 035: Affirmative Action and Nondiscrimination in Employment: https://www.ucop.edu/academic-personnel-programs/_files/apm/apm-035.pdf