Economic Modelling Scientist

417768 Economic Modelling Scientist

ViiV Healthcare is an independent, global specialist HIV company that is committed to delivering innovative new options for HIV prevention and in the care and treatment of people living with HIV/AIDS. ViiV is 100% dedicated to HIV medicines and research, and completely focused on people affected by HIV/AIDS.

For drugs to be successful, there must be robust health outcomes data to support launch optimization, reimbursement and maintain market position. Specifically, evidence must be maintained throughout the product lifecycle as standard of care changes and new competitors are introduced. The current and developing ViiV portfolio requires significant HEOR input both for market access/reimbursement for current and future launches, as well as evidence generation for lifecycle management.

The role of the Associate Director, Modelling is essential to ensuring that each medicine brought to market is supported by scientifically credible, high quality, evidence aligned with the needs of decision makers responsible for granting access / reimbursement, whilst providing leadership in a particular therapy area (here supporting HIV/ViiV Healthcare). The Associate Director, Modelling works in collaboration with colleagues across data generation, Medical, Biostatistics, Epidemiology, and other parts of GSK/ViiV to apply specialized expertise in modelling to support the development of Health Technology Assessment (HTA) reimbursement strategy, core economic models (cost effectiveness and budget-impact) and robust methods for generating appropriate model data inputs. The evidence generated from this work informs drug development, supports HTA reimbursement submissions, informs health care providers, and ultimately, serves to transform clinical practice and improve the outcomes of people living with HIV.

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In this role you will

The role will serve as single point accountable Modelling Lead for a number of projects supporting assets within the HIV therapy area. The role will be accountable for ensuring close engagement with medical and matrix stakeholders and partner effectively in integrated evidence planning, design, execution, translation and dissemination of evidence for the asset and to ensure the highest standards of excellence are applied to modelling projects from a scientific/technical perspective. The responsibilities listed below outline the scope of the position, but may vary, based upon evolving business needs.

• Partner effectively with matrix stakeholders in planning and design of the Integrated Evidence Plan for the asset, drive disciplined execution of studies and activities, translate results and disseminate data and research findings to all relevant internal and external stakeholders.
• Drive innovation and inform ideas and options through effective engagement with external experts, clinical guideline groups, HTA agencies, methodology and policy forums, and by leveraging knowledge of the external policy and decision maker environment to enable more efficient evidence development for the asset across the lifecycle (e.g. discovery, launching and life cycle management assets).
• Propose fit-for-purpose modelling/ HE solutions to asset teams, the broader data generation / Medical community, and/or bring the necessary expertise to a matrix team to proactively influence evidence generation through analytics, standards, innovation, and best practices.
• Supervise the technical aspects of developing core economic models for medicines preparing for launch/HTA reimbursement applications, in cooperation with key individuals within Market Access and with vendors.
• Lead development of global models for medicines preparing for launch/HTA reimbursement applications, alongside vendors as relevant, in collaboration with Medical, Development, data generation, Epidemiology.
• Develop early economic models for pipeline products to be shared with product development teams to inform clinical development plans including Phase III trial design and real-world studies.
• Serve as a member of the Modelling Protocol Review Committee to peer review modelling protocols submitted by global teams as well as Local Operating Companies (LOCs) seeking to undertake their own analyses.
• Quality-assure economic modelling deliverables of external vendors, ensuring transparency and adherence to best-practice by recognized industry standards.
• Negotiate with key stakeholders as to what evidence for the asset is and is not developed, weighing risks and benefits to optimize reimbursement opportunities, support scientific exchange and clinical guideline development.
• Facilitate alignment and partnership to enable more effective interactions within the complex stakeholder matrix, e.g. clinical, commercial, market access, medical affairs functions, priority market LOCs as well as external third-party suppliers.
• Define and lead delivery of internal Modelling initiatives (e.g., technical or process improvement initiatives).
• Maintain currency with innovative and novel methods for Modelling.
• Develop standardized tools and templates to streamline the economic modelling development process and ensure minimum quality standards are met consistently.
• Prepare relevant sections of documentation and communication for scientific advice meetings; participate and represent organization at such meetings.
• Prepare abstracts and manuscripts as part of a defined Data Dissemination Plan for assets and to showcase any research developed over the course of supporting an asset or as independent methods research.
• Participate in external engagement to stay abreast of best practices in economic modelling and create network of experts with whom to share innovations in methods.
• Drive discipline in performance reporting and ensure studies are delivered according to plan and within budget.

Why you?

Basic Qualifications & Skills:

We are looking for professionals with these required skills to achieve our goals:

• Advanced degree in a relevant health discipline, such as, but not limited to health outcomes research, health economics, economics, and mathematical modelling to inform health policy.
• Significant and varied experience working in epidemiology, outcomes/health economics research, market access and/or and policy related to use of epidemiology, RWE, or health outcomes/economics for submission to regulatory agencies and/or HTAs. Preferably in the biopharmaceutical industry, pharmaceutical services sector (consulting), and/or a regulatory agency.
• Experience conducting adaptations of economic models to local country settings, including validation of underlying clinical proposition as well as sourcing of model inputs.
• Experience leading the economic section of an HTA submission including an economic model in more than three markets.
• Significant experience of independently led hands-on development of economic models within a consultancy environment, academia or pharmaceutical company.
• Experience drafting technical reports for complex economic models with clear written English and attention to detail, including complete referencing using suitable referencing software or tools.
• Authorship of publications detailing cost-effectiveness modelling research.
• Good understanding of evolving HTA methodologies and health system environments.
• A good understanding of drug development processes and strategies, with proven ability to apply innovative thinking to meet project and/or business objectives.
• Excellent problem-solving and analytical skills, including finding efficient and innovative solutions to challenging problems.

Preferred Qualifications & Skills:

Please note the following skills are not necessary, just preferred, if you do not have them, please still apply:

• Prior experience or knowledge of the HIV field, other infectious diseases, or in transmission modelling, would be desirable but not essential.
• Self-motivated with the ability to work independently to develop credibility with colleagues.
• Excellent communication skills to interact effectively in multi-disciplinary matrix teams and to influence global stakeholders and key opinion leaders.
• Ability to work well within a business-driven environment, establish cross-functional relationships, balance priorities and handle multiple tasks through good planning, project administration, and organization skills.
• Significant experience working within all MS office applications with a particular emphasis on Excel. Knowledge of programming languages such as R would be desirable.
• Experience working in a fast-paced environment with multiple completing priorities.

Closing Date for Applications - June 8th, 2025 (COB)

Please take a copy of the Job Description, as this will not be available post closure of the advert.

When applying for this role, please use the 'cover letter' of the online application or your CV to describe how you meet the competencies for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

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