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Senior HPC Engineer Applications

Genentech
United States, California, South San Francisco
May 16, 2025
The Position

We advance science so that we all have more time with the people we love.

Are you a High Performance Computing (HPC) Engineer that would like to help advance new treatments for cancer and infectious disease? The Genentech Computational Sciences Infrastructure & Architecture department seeks a talented and motivated HPC Engineer to lead our efforts delivering and supporting scientific applications and workflows on our cloud-based and on-premises HPC platforms.

The job will utilize and build on your prior experience building, testing, delivering, and supporting scientific computing software in HPC environments. The work will require technical leadership across globally distributed teams, advocacy for best engineering practices, and some hands-on software development.

The Opportunity:

As part of our HPC team specializing in applications and workflow, you will guide our approaches to delivering and supporting:

  • Common open source and commercial scientific software codes used in HPC

  • High-level programming languages used in science, including Python and R

  • Software packaging and deployment tools, including Easybuild, Spack, and software containers

  • Software environment management tools, including conda and pip/venv

  • Work directly with and support HPC usersand collaborate with internationally distributed teams

  • Apply and advocate for engineering best practices and communicate effectively in both written and verbal form to non-technical audiences

Who You Are:

  • 4+ years of related experience supporting scientific computing and/or high performance computing (HPC) platforms

  • 4+ years of education (or equivalent experience) with computer science, information systems, engineering, or life/physical sciences preferred

  • Experience compiling, delivering, and supporting software codes on an HPC cluster

  • Solid engineering and coding skills, and ability to write quality code/scripts. Prior experience with Python and Bash is a must

  • Solid understanding of Linux operating system fundamentals

  • Basic understanding of HPC schedulers, job optimization, and best practices

  • Experience in working with source control management systems such as Git

Preferred Qualifications:

  • Experience with R programming language/ecosystem, Posit tools and associated software packaging tools such as EasyBuild, Spack, and Homebrew

  • Experience with DevOps software engineering practices, including continuous integration and testing frameworks

  • Experience with infrastructure and software delivery platforms such as the CernVM File System, AWS public cloud platforms and managed services

  • Experience as an informatics/DevOps technical team lead in the Pharma/Biotech industry

Relocation benefits are not available for this posting.

Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week for local candidates. For a strong non local candidate, we are open to this being a remote-based opportunity.

The expected salary range for this position based on the primary location of California is $142,500 - $264,700 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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#I&A

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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