Principal Scientist 1

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

This role is a valuable part of our Research and Early Development Chapter and is the home for early research activities within the Diagnostics organization. We are organized in chapters to address discovery and specific customer area needs. We use the OneRoche approach to rapidly deliver innovation and more importantly, doing what the patient needs next.

• This position requires that you are onsite 5 days a week in Pleasanton, CA

The Opportunity:

You will be joining a team of passionate scientists and engineers within the Research and Early Development chapter area in the broader Roche Diagnostic organization to drive the discovery and development of innovative solutions that have real impact on people's lives. The Principal Scientist I brings technical depth and breadth, curiosity, and creativity to be an important contributor in developing novel molecular diagnostic applications at the point-of-care. Collaborating with a team with unique backgrounds, you will work hands-on in the laboratory through all research and early development phases, from exploratory research to prototype transfer

• Designs, plans and implements experiments applying established and innovative procedures, and applying scientific knowledge and accumulated experience to complete projects.

• Contributes to the definition and timely achievement of overall project goals, and resolves scientific problems encountered during experimental procedures to improve productivity of results.

• Ensures activities are consistent with project critical path, and responds appropriately to changing priorities.

• Accurately and consistently records experimental methods, materials and results in electronic laboratory notebooks.

• Analyzes data, evaluates results, forms conclusions and implements/documents process improvements.

• Integrates previous and current results to determine next experimental steps and the impact of long-range project goals.

• Presents findings at group or departmental meetings. Applies advanced technical writing skills to produce reports and documents. May assist in preparing summaries, memos, internal reports, presentations, manuscripts, etc.

• Work involves troubleshooting and resolving difficult problems in creative ways. Takes a new perspective on existing solutions, exploring and implementing new concepts and methodologies.

• May supervise junior scientists/research associates.

Who You Are:

• You have a PhD in life sciences: Biology, Chemistry, Biochemistry, Microbiology, Bioengineering, or related field with 6+ years experience in an industry setting

• You have 6 years of hands-on experience working in a laboratory to execute experimental designs/studies.

• You are proficient with molecular biology techniques such as PCR, qPCR, or isothermal-based nucleic acid amplification.

• You can apply in-depth molecular biology knowledge and experience in the development of CRISPR-based molecular diagnostic assay, including development of novel CRISPR proteins, reaction reagents, assay workflow integrations.

Preferred Qualifications:

• You have experience with molecular point-of-care IVD assay development including but not limited to sample preparation, sample enrichment, assay chemistry optimization, assay workflow, and instrumentation

• You have experience handling and testing of viral and bacterial samples

• You have familiarity with developing molecular diagnostic products in an IVD or CLIA setting

The expected salary range for this position based on the primary location of Pleasanton, CA is $108,400-201,200. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed here: Benefits

Relocation benefits are not available for this position

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.