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Bioinformatics Specialist II

Massachusetts General Hospital
United States, Massachusetts, Boston
265 Charles Street (Show on map)
Jul 16, 2025
Summary
Responsible for combining research in biology, medicine, and health-related studies with information technology in order to collect and interpret data covering a range of fields, such as genetics or pharmaceutics. This role creates mathematical models, develop dynamic simulations, and perform pattern analyses of biological systems.
Essential Functions
Independently design and execute bioinformatics analyses and research projects on small-mid scale projects.
Develop and optimize data analysis pipelines and workflows.
Collaborate with scientists and researchers to define analysis goals and interpret results.
Provide technical expertise and support for bioinformatics tools and software.
Train junior scientists and provide technical guidance.
Analyze data quality and integrity of data output from existing algorithms as part of the complex, multi-step specimen tracking and reporting process, across multiple systems and web-based interfaces.
Develop new and innovative tools to enhance quality assurance review and to improve assay and system performance.
Design and apply novel computational methods/bioinformatics algorithm, machine learning models for building data models and tools using various software and statistical tools to aid in the analysis and interpretation of genetic data, clinical data, images (NGS Algorithm development, Machine Learning).
Analyze large molecular datasets of tumor sequencing data to help critically review and analyze the results of specimen testing, working closely with faculty and staff to troubleshoot problems, recommend technology-based solutions, or determine computational strategies.
Required for All Jobs
Performs other duties as assigned
Complies with all policies and standards
Does this position require Patient Care (indirect/direct)? No

Education

Master's Degree Computational Biology preferred or

Bachelor's Degree Computational Biology required

Can this role accept experience in lieu of a degree? Yes

Experience

Computational Sciences Experience 3-5 years required

Knowledge, Skills & Abilities

Demonstrated experience in infrastructure, programming languages and computational sciences.

Demonstrated ability working with open-source bioinformatics software.

Possess strong analytical skills including critical thinking, data modeling, problem solving and troubleshooting.

Strong organizational and interpersonal skills.

Ability to effectively communicate, both orally and in writing, to all levels of staff.

Excellent time management skills.

Physical Requirements

Standing Occasionally (3-33%)
Walking Occasionally (3-33%)
Sitting Constantly (67-100%)
Lifting Occasionally (3-33%) 20lbs - 35lbs
Carrying Occasionally (3-33%) 20lbs - 35lbs
Pushing Rarely (Less than 2%)
Pulling Rarely (Less than 2%)
Climbing Rarely (Less than 2%)
Balancing Occasionally (3-33%)
Stooping Occasionally (3-33%)
Kneeling Rarely (Less than 2%)
Crouching Rarely (Less than 2%)
Crawling Rarely (Less than 2%)
Reaching Occasionally (3-33%)
Gross Manipulation (Handling) Constantly (67-100%)
Fine Manipulation (Fingering) Frequently (34-66%)
Feeling Constantly (67-100%)
Foot Use Rarely (Less than 2%)
Vision - Far Constantly (67-100%)
Vision - Near Constantly (67-100%)
Talking Constantly (67-100%)
Hearing Constantly (67-100%)



The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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