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Staff Scientist, Bioinformatics (Hybrid)

Quest Diagnostics Incorporated
$114,000.00 - $134,000.00 / yr
flex time, 401(k)
United States, Massachusetts, Marlborough
Oct 23, 2025
Job Description

Pay Range: $114,000.00 - $134,000.00 / year

Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, where applicable, certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.

Benefits Information:

We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy, happy lives. Our pay and benefit plans have been designed to promote employee health in all respects - physical, financial, and developmental. Depending on whether it is a part-time or full-time position, some of the benefits offered may include:

* Day 1 Medical, supplemental health, dental & vision for FT employees who work 30+ hours

* Best-in-class well-being programs

* Annual, no-cost health assessment program Blueprint for Wellness

* healthyMINDS mental health program

* Vacation and Health/Flex Time

* 6 Holidays plus 1 "MyDay" off

* FinFit financial coaching and services

* 401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service

* Employee stock purchase plan

* Life and disability insurance, plus buy-up option

* Flexible Spending Accounts

* Annual incentive plans

* Matching gifts program

* Education assistance through MyQuest for Education

* Career advancement opportunities

* and so much more!

Complete oversight of BME operations for large, complex sites and/or multiple sites to ensure service program efficiency and to satisfy the equipment support needs of the company.

The purpose of the BME Sr. Manager position is to develop, coordinate, and expand the BME program as necessary to ensure all aspects of service (internal and external) for all lab instrumentation and general lab equipment satisfy the quality and regulatory requirements and service needs for each lab, enabling operations to run efficiently, profitably, and with excellent quality.

We are a leading oncology diagnostics company dedicated to advancing precision medicine through cutting edge ultra-sensitive genomic technologies. As we expand our portfolio of minimal residual disease (MRD) testing solutions, we are seeking a highly skilled and motivated Bioinformatics Scientist to join our team. This role offers the opportunity to contribute to the development and implementation of bioinformatics methods that directly impact cancer patient care, enabling improved monitoring, and more informed treatment decisions.

Description:

  • The staff bioinformatics scientist will serve as a key technical contributor in the design, development, and implementation of bioinformatics pipelines and analytical methods to support MRD testing and other NGS assays.

  • The ideal candidate will bring expertise in NGS data analysis, statistical modeling, and computational biology, with the ability to translate complex genomic data into operationally and clinically meaningful insights.

  • This role will involve close collaboration with wet lab scientists, clinical operations teams, R&D teams, and software engineers to ensure high quality, accurate, reliable, and scalable solutions for patient testing and reporting.

This professional will work in a hybrid capacity requiring 3 days onsite per week at our Marlborough, MA facility.



Responsibilities:
  • Design, develop, and optimize bioinformatics pipelines for MRD test development and clinical deployment.

  • Analyze high throughput NGS data and drive performance and scientific insights to support research and development of on-market and upcoming products.

  • Collaborate with laboratory scientists, clinicians, and software engineers to validate and integrate bioinformatics solutions into clinical workflows.

  • Support regulatory and quality documentation, including validation reports, standard operating procedures, and compliance with CLIA/CAP and other quality and regulatory standards.

  • Provide scientific and technical leadership in bioinformatics, mentoring junior team members and guiding best practices.

  • Stay current with advancements in oncology genomics, liquid biopsy, and computational biology methods to inform innovation and future product enhancement.

  • Identify problems, investigate alternatives and recommend possible courses of action, contribute to technical decisions.

  • Prepare and present information at project meetings, scientific & technical meetings/conferences, and to customers.



Qualifications:

Required Work Experience:

  • Ph.D. or M.S. with extensive industry experience.

  • 5+ years of hands-on experience analyzing NGS data, preferably in oncology diagnostics.

  • Strong programming skills in Python, R, or equivalent platforms.

  • Strong logical reasoning skills, with desire to drive solutions for some of the most challenging problems in the field of oncology diagnostics.

  • Proven expertise in variant calling, error suppression, and ultra-sensitive detection of low-frequency variants.

  • Expertise with cloud based computational environments (AWS, or similar).

  • Demonstrated ability to work with regulated clinical or diagnostic environments (e.g., CLIA, CAP, or FDA submissions)

Preferred Work Experience:

  • Ph.D in Bioinformatics, computational biology, genomics, or related fields

Physical and Mental Requirements:

  • Sitting for long periods at a time.

  • Maintain composure under pressure

  • Adapts to change

  • Ability to grasp information quickly

  • Ability to multi-task

  • Ability to follow verbal or written instructions

  • Using effective verbal communication

  • Think analytically

  • Using effective written communication

  • Handle stress & emotions

  • Concentrate on tasks

  • Making decisions

  • Adjust to change

  • Examine/observe details

Knowledge:

  • Requires knowledge and skills normally acquired through the successful completion of an advanced degree (M.S./Ph.D.) in Genomics, Computational Biology, Computer Science, or related scientific discipline.

  • Knowledge of related products and technologies - academic or industrial setting

Skills:

  • Mathematical Skills, Reasoning Ability

  • Ability to read and interpret documents such as professional journals, operating instructions, and procedure manuals. Ability to write complete reports and correspondence. Ability to speak effectively in one-on-one and small group situations including teleconferenced/remote participants.



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Quest Diagnostics honors our service members and encourages veterans to apply.

While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.

Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.
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