Open Rank

A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation's top public universities. Known for its beautiful campus, world-class medical care, commitment to the arts and top athletic programs, Carolina is an ideal place to teach, work and learn.

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The University of North Carolina at Chapel Hill School of Medicine invites applications for a full-time fixed term faculty open rank position to lead proteomics initiatives within the UNC Metabolomics and Proteomics ( MAP) Core Facility. Operating within the Department of Pharmacology, the MAP Core is a university-operated recharge center offering state-of-the-art mass spectrometry-based proteomics and metabolomics services to internal and external collaborators. As a full-service facility, we support every stage of project execution from consultation and sample preparation to mass spectrometry acquisition and data analysis, using advanced instrumentation, including Thermo Orbitrap Astral, Exploris 480, and Q Exactive HF mass spectrometers; multiple LC platforms (Thermo Vanquish Neo, Ultimate 3000, Evosep One); CE systems (908 Devices ZipChip); an Agilent offline HPLC fraction collector; and automated sample preparation platforms (Seer One and Thermo Accelerome).

The successful candidate will help maintain and establish collaborative research projects, support grant funding efforts (e.g., NIH, NSF), contribute to publications in leading journals, and advance the department's educational and research mission while fostering interdisciplinary collaborations across the university.
Initial consideration will be given for applications submitted by February 1, 2026.

Ph.D. in Biochemistry, Chemistry, Pharmacology, or a related discipline, with demonstrated hands-on experience in proteomics and mass spectrometry.
Current Assistant and Associate Professors are welcome to apply.
Minimum of 3 years of relevant research experience in proteomics and mass spectrometry.
Hands-on expertise with LC-MS instrumentation (Thermo Orbitrap systems, nanoLC platforms).
Proficiency in proteomics software (Proteome Discoverer, MaxQuant, Skyline, Spectronaut).
Experience with quantitative proteomics approaches ( TMT, SILAC, label-free).

Experienced in overseeing and advancing complex proteomics projects, including global quantitative proteomics, phosphoproteomics, PTM analysis, and chemoproteomics.
Proficient in developing, optimizing, and troubleshooting LC-MS workflows and instrumentation, demonstrating expert-level problem-solving for complex systems.
Knowledgeable in statistical and bioinformatics tools (R, Python preferred), as well as integrating proteomics with multi-omics strategies to support high-impact collaborative research initiatives.
Skilled in mentoring and guiding junior scientists and technical staff in proteomics methods and data analysis, fostering technical excellence and team growth.
Proven track record in contributing strategically to grant proposals, manuscripts, and the development of proteomics capabilities, showcasing strong communication and organizational leadership.
Prior experience working in a core facility or highly collaborative research environment.
Advanced troubleshooting skills for complex LC-MS instrumentation and related technologies.
Excellent communication and organizational skills to foster collaboration, manage projects, and support grant development.

The University is an equal opportunity employer and welcomes all to apply without regard to age, color, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, or sexual orientation. We encourage all qualified applicants to apply, including protected veterans and individuals with disabilities.