New

Biologist

Spectraforce Technologies
United States, Massachusetts, Worcester
Jan 02, 2026
Position Title: Biologist Work Location: Worcester, MA Assignment Duration: 06 Months Work Schedule: Monday-Friday, 9:00 AM-5:00 PM Work Arrangement: Onsite Position Summary: The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated and energetic bioanalytical scientist to join the biologics bioanalysis, characterization and proteomics (BBCP) group. The primary responsibility of this position is to support LC-MS (liquid chromatography-mass spectrometry)-based bioanalysis and method development for biologic entities, such as monoclonal antibodies, multi-specific antibodies, antibody-drug conjugates (ADCs), and other novel modalities. Key Responsibilities: Perform affinity purification and digestion of biological therapeutics (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices manually or using automation systems. Operate and maintain LC/MS instruments to generate high-quality experimental data. Optimize and develop LC/MS methods to meet assay specificity and sensitivity requirements. Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks. Communicate data interpretation internally and externally. Qualifications & Experience: Degree in chemistry, pharmacology or other related fields. BS with 5+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry. Prior industry experience in drug discovery/development is highly desired. Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor. Hands-on experience with QQQ (SCIEX) is required, additional experience with qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is a plus. Hands-on experience with biologics bioanalysis is highly desired, additional experience with oligonucleotide analysis is a plus. Hands-on experience with immuno-affinity purification and automation systems (e.g., TECAN, AssayMap Bravo or Hamilton) is highly desired. In-depth understanding of PK, TK and PK/PD studies is preferred.