Assistant Professor - Hematology, Oncology & Transplantation

The Division of Hematology, Oncology and Transplantation at the University of Minnesota Medical School is seeking a non-tenure-track Assistant Professor on the Research Track with expertise in translational cancer research, extracellular vesicle biology, mass spectrometry-based proteomics, liquid biopsy, and biomarker development.

Position Responsibilities

The successful candidate will:

* Develop and lead an innovative translational research program centered on extracellular vesicles, circulating biomarkers, cancer proteomics, and precision oncology.

* Identify and validate blood-based biomarkers associated with cancer progression, treatment response, therapeutic resistance, and clinical outcomes, using clinically annotated patient specimens.

* Develop, optimize, and benchmark extracellular vesicle enrichment and isolation strategies suitable for large clinical cohorts, and apply them to proteomic and multiomic molecular characterization of cancer.

* Apply discovery and targeted mass spectrometry, including high-resolution data-independent acquisition workflows and post-translational modification analysis such as phosphoproteomics and glycoproteomics, to the characterization of circulating and vesicle-associated proteins with potential clinical utility.

* Integrate proteomic findings with genomic, transcriptomic, imaging, and clinical data to define biologically and clinically relevant cancer phenotypes, including through survival and outcome associated analyses.

* Investigate molecular mechanisms underlying treatment sensitivity and resistance, including mechanisms relevant to systemic therapy, targeted therapy, radiopharmaceutical therapy, and immune-directed agents.

* Examine interactions between tumor-derived extracellular vesicles, effector and suppressive immune populations, and other components of the tumor microenvironment, including vesicle-associated immune checkpoint and glyco checkpoint ligands.

* Develop and analytically evaluate biomarker assays that may support patient stratification, treatment selection, disease monitoring, and therapeutic development, with attention to sensitivity, reproducibility, and clinical interpretability.

* Conduct preclinical and translational studies that establish the biological relevance of candidate biomarkers using cancer cell models, molecular perturbation approaches, and patient-derived material.

* Establish and pursue additional experimental avenues that advance the development and clinical application of liquid biopsy and proteomic technologies in hematologic malignancies.

* Collaborate with faculty within the Division of Hematology, Oncology and Transplantation, the Masonic Cancer Center, and across the University of Minnesota on multidisciplinary translational research programs, and contribute scientific expertise to correlative studies embedded within investigator-initiated and industry-sponsored trials.

* Develop an increasingly independent and externally funded research program consistent with expectations of the Research Track.

* Disseminate research findings through peer-reviewed publications, scientific presentations, and participation in national and international scientific meetings.

* Supervise and mentor research personnel and contribute to the training of graduate students, postdoctoral fellows, medical trainees, and other postgraduate researchers in translational oncology, proteomics, extracellular vesicle biology, and biomarker research.

Required Qualifications

Candidates must have:

* A doctoral degree such as an MD, PhD, MD/PhD, or equivalent degree in medicine or a relevant biomedical or scientific discipline.

* Successful completion of postdoctoral research training.

* Relevant research experience in laboratory-based preclinical and translational cancer research.

* Demonstrated expertise in extracellular vesicle biology, liquid biopsy, cancer proteomics, and biomarker development, supported by a record of peer-reviewed publications.

* Strong working knowledge of mass spectrometry-based proteomic workflows, including sample preparation, data-independent acquisition, spectral library generation, and quantitative downstream analysis.

* Experience working with clinically annotated biospecimens and integrating laboratory findings with clinical outcomes.

* Experience conducting studies investigating mechanisms of cancer progression, therapeutic response, or treatment resistance.

* Experience supervising research personnel and contributing to the training and development of students or other research trainees.

* Demonstrated ability to work effectively within multidisciplinary and collaborative research environments, including partnerships with clinical investigators, biostatisticians, and industry collaborators.

* Ability to obtain and maintain appropriate authorization to work in the United States.

Pay Range: $90,000-$115,000; depending on education/qualifications/experience

Time Appointment: 100% Appointment

Position Type: Faculty and P&A Staff

Please visit the Office of Human Resources website for more information regarding benefit eligibility.

The University offers a comprehensive benefits package that includes:

• Competitive wages, paid holidays, and generous time off
• Continuous learning opportunities through professional training and degree-seeking programs supported by the Regents Tuition Benefit Program
• Low-cost medical, dental, and pharmacy plans
• Healthcare and dependent care flexible spending accounts
• University HSA contributions
• Disability and employer-paid life insurance
• Employee wellbeing program
• Excellent retirement plans with employer contribution
• Public Service Loan Forgiveness (PSLF) opportunity
• Financial counseling services
• Employee Assistance Program with eight sessions of counseling at no cost
• Employee Transit Pass with free or reduced rates in the Twin Cities metro area

While our salary ranges provide a framework, it is important to note that most of the
time, the initial pay may not reach the maximum of the range. This approach ensures
that compensation reflects the value and unique contributions of each candidate while
maintaining equity within our organization. As part of our commitment to fair and
equitable compensation, please be aware that the salary offered to incoming candidates
will be based on their individual credentials and experience.

Applications must be submitted online. To be considered for this position, please click the Apply button and follow the instructions. You will have the opportunity to complete an online application for the position and attach a cover letter and resume or CV.

This position will remain open until filled.

To request an accommodation during the application process, please e-mail jobcentr@umn.edu.

The University recognizes and values the importance of diversity and inclusion in enriching the employment experience of its employees and in supporting the academic mission. The University is committed to attracting and retaining employees with varying identities and backgrounds.

The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. To learn more about diversity at the U: http://diversity.umn.edu

Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.

The University of Minnesota, Twin Cities (UMTC)

The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.

At the University of Minnesota, we are proud to be recognized by Forbes as a Best Employer for Company Culture (2026), Best Employer for Women (2023, 2025, 2026), and Best Employer by State (2022-2026). In 2026, we also received Culture Excellence & Industry Awards recognition for employee appreciation and work-life flexibility.

About the U of M Medical School:

Committed to innovation and diversity, the Medical School educates physicians, scientists, and health professionals; generates knowledge and treatments; and cares for patients and communities with compassion and respect. We value excellence, inclusiveness, collaboration, and discovery.

The mission of the regional campus located in Duluth is to be a national leader in improving healthcare access and outcomes in rural Minnesota and American Indian/Alaska Native (AI/AN) communities. In partnership with CentraCare, the regional campus in St. Cloud offers a wide range of patient experiences throughout students' education in Greater Minnesota and prepares them to become exceptional clinicians and leaders for rural and immigrant populations.

Founded in 1888, the University of Minnesota Medical School has three campuses. A four-year MD program and the MD/PhD program are located on the Twin Cities campus in addition to MD programs at regional campuses in Duluth and St. Cloud.