Post-Doctoral Fellow

University of Colorado | CU Anschutz Medical Campus

Department of Pathology

Postdoctoral Fellow

* Applications are accepted electronically ONLY at www.cu.edu/cu-careers *

The University of Colorado has a requirement for COVID-19 vaccinations and full completion thereof by 9/1/21 or upon start date. Information regarding this requirement, and exemptions can be found at:

Anschutz: https://www.ucdenver.edu/docs/librariesprovider284/default-document-library/3000-general-admission/3012---covid-19-vaccination-requirement-and-compliance.pdf?sfvrsn=4e9df3ba_2

Exemptions vary by campus location/department.

Campus/Unit-Specific Exemptions:

• Anschutz Campus - Exemptions are allowed for medical or religious reasons.
• Consolidated/Central Services Administration - Will follow Anschutz policy on exemptions.

The University of Colorado Anschutz Medical Campus seeks individuals with demonstrated commitment to creating an inclusive learning and working environment. We value the ability to engage effectively with students, faculty and staff of diverse backgrounds.

Full time- postdoctoral fellow position available for self-driven and curious candidates with a fresh PhD in Biochemistry, Molecular/ cell Biology, Cancer Biology or Neuroscience to join the laboratory in the Department of Pathology, School of Medicine, University of Colorado Anschutz Medical Campus (Aurora, CO, USA). This position will provide a unique opportunity to be part of an enthusiastic research team working towards increasing survival for brain metastasis patients both through basic and translational research. Our goal is to unveil the mechanisms that allow cancer cells to spread to and colonize the brain and to discover novel therapeutic strategies for brain metastases. Ongoing projects include: 1) Defining how estrogens modulate the brain niche (immune cells, astrocytes, microglia) to promote brain metastases progression in younger women; 2) Defining mechanisms for progression of brain metastasis in the aging brain; 3) Preclinical targeting of receptor tyrosine kinases from the prevention or treatment of breast and lung metastasis.

To achieve our goal, we use a variety of neuroscience, molecular biology, cell and tissue imaging and in vivo modeling of metastasis. We work in close collaboration with neurosurgeons and oncologists so we are looking for a team-member who enjoys communication with people from diverse backgrounds. The postdoctoral fellow should have demonstrated experience in tissue culture of primary glial and neuronal cells, basic molecular biology, IF, IHC imaging and confocal microscopy. This fast-paced field will provide the candidate with opportunities for innovation, high impact research and personal and professional growth. As such, the postdoctoral fellow should demonstrate desire to learn, superb organizational skills, ability to prioritize and make decisions, be a problem-solver and innovator with a big dose of self-motivation. The successful candidate will be expected to lead and develop projects and perform independent experiments with a focus on glia-neuron-cancer cell interactions during brain metastatic progression.

Job Description/Duties:

Primary activities in the lab includes, but are not limited to:

• Performing preclinical studies with brain metastasis patient-derived cancer cells and cancer cell lines in vivo. Isolation and characterization of cancer and brain cell populations from clinical samples and mice, tissue labeling and imaging.
• In vitro cell culture and cell-based assays, standard molecular and biochemistry techniques.
• Work independently after initial training with minimum supervision.
• Design, execute and interpret experiments.
• Write grants and manuscripts, and present at scientific conferences.
• Contribute to maintain a high standard of quality and cleanliness in the lab.
• Maintain updated notebooks and relevant databases, present progress reports.

Salary and Benefits:

The hiring salary is $ 53,760 -$63,036 . This position is not eligible for overtime compensation.

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.

The University of Colorado offers a full benefits package. Information on University benefits programs, including eligibility, is located at Employee Services.

University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background checks for all new employees prior to their employment.

The Immigration Reform and Control Act requires that verification of employment eligibility be documented for all new employees by the end of the third day of work. Alternative formats of this ad are available upon request for persons with disabilities.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.

Benefits: https://www.cu.edu/employee-services/benefits.

Total Compensation Calculator: https://www.cu.edu/employee-services/total-compensation

Diversity and Equity:

Please contact hr.adacoordinator@ucdenver.edu for information on disability accommodations

Office of Equity: https://www1.ucdenver.edu/offices/equity

The University of Colorado Denver | Anschutz Medical Campus is committed to recruiting and supporting a diverse student body, faculty and administrative staff. The university strives to promote a culture of inclusiveness, respect, communication and understanding. We encourage applications from women, ethnic minorities, persons with disabilities and all veterans. The University of Colorado is committed to diversity and equality in education and employment.

The University of Colorado Denver | Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.

Minimum Qualifications:

* A Ph.D. degree in biomedical sciences with background in cancer biology or neuroscience is required

* Experience in WB, qRT-PCR, IHC/IF, imaging, cloning, mammary cell culture, transduction/transfection are required.

* Records of first author manuscripts in peer-reviewed journals.

Preferred Qualifications:

* Experience with flow cytometry and/or multiparametric IF staining and analysis

* Experience in breast or lung cancer biology, cloning and genetic engineering, flow cytometry

Knowledge Skills, Abilities:

• Have demonstrated experience with mammalian tissue culture, basic molecular biology techniques. Experience with flow cytometry is not required but would be a plus.
• Have excellent communication skills and the ability to work independently as well as part of a team.
• Ability to execute and prioritize multiple tasks simultaneously. Be open to learn new methods to achieve high performance while enjoying life.
• Natural curiosity. Ability to design and perform experiments, develop, and learn new techniques, critically interpret experimental results, and present data
• Intrinsically self - driven and forward focused, does not need constant external motivation
• Ability and desire to participate in the preparation of grant applications and publications
• Know how to operate Microsoft office, graphpad/Prism, analyze flow cytometry data.
• Ability to mentor others in lab-related activities.
• Ability to communicate effectively, both in writing and orally.
• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution.
• Be eager to learn, wants to take leadership of his/her/their projects.

Applicants must meet minimum qualifications at the time of hire.

1. A letter of application which specifically addresses the job requirements and outlines qualifications
   
2. A current Resume/CV
   
3. The names, addresses, daytime telephone numbers and e-mail addresses for three professional references, either attached to your resume/CV or uploaded as a separate document