Sr. Manager, Sample Management

The Senior Manager of Sample Management provides expertise to the Research and Early Development (ReDEV) organization. Reporting to the Director of Lab Operations, the Senior Sample Operations Manager will work closely with ReDEV scientists, partners, global trade, compliance, shipping team, supply chain and CROs on coordinating operational activities for the handling, shipping, tracking, storing and transferring of biological materials and test/control articles in ReDEV within the laboratory information management system (LIMS).

This position is onsite and will be in Cambridge, MA.

Key Responsibilities

* Develop and lead the ReDEV Sample Management team.
* Oversee and manage the day-to-day operations of the biorepository, including sample collection, processing, storage, tracking, and distribution using LIMS.
* Manage and monitor sample transfers between departments, shipping, CROs, and offsite storage.
* Manage offsite sample inventory and coordinate transfers to and from onsite laboratories.
* Serve as the subject matter expert (SME) for all repository related aspects that include the usage of LIMS, inventory and shipping of samples.
* Work with ReDEV teams to organize and catalog existing freezers using the Alnylam LIMS (Sapio, LabWare, and Watson).
* Develop and implement standard operating procedures (SOPs) and Work Instructions to ensure compliance with the sample retention, quality, integrity, and traceability.
* Implement a sample retention policy to support the disposition of samples.
* Oversee the management of the LIMS ensuring accurate tracking of biological materials, test articles, other samples and metadata.
* Develop processes, procedures, and report requirements and work with the ReDEV Software Engineering and IT teams to support the sample management team.
* Develop metrics and provide regular reporting to improve sample management processes and workflows.
* Stay current with advancements and best practices in biorepository management and recommend improvements to enhance efficiency and effectiveness.
* Maintain records of all biosafety and biosecurity measures, including hazardous material handling and disposal where applicable.
* Supervise and provide training to sample management staff, ensuring adherence to SOPs, Work Instructions, and safety protocols.
* Provide ongoing training and development opportunities for staff to keep up with evolving technologies and new systems.
* Other duties related to the job function may be requested.

Qualifications

* University Science Degree with a minimum of 8 years of sample management/operations experience in academic or industry setting.
* Strong experience using a biorepository system/ LIMS.
* Previous experience managing and coordinating domestic and international shipments.
* Previous experience in handling biological specimens and managing large inventories in a lab setting.
* Demonstrated ability to work in a dynamic environment with a sense of urgency and creativity and focus on deliverables.
* Strong knowledge of regulatory and compliance requirements (e.g., FDA, GLP, GMP, HIPAA) and industry best practices for tracking, handling and storing samples.
* Excellent organizational skills with attention to detail and a commitment to maintaining accurate records.
* Ability to communicate effectively with external and internal teams.
* Strong problem-solving skills with the ability to balance multiple projects simultaneously.
* Ability to work independently with minimal oversight.

About Alnylam:Alnylam Pharmaceuticals (Nasdaq: ALNY) has led the translation of RNA interference (RNAi) into a whole new class of innovative medicines with the potential to transform the lives of people afflicted with rare and more prevalent diseases. Based on Nobel Prize-winning science, RNAi therapeutics represent a powerful, clinically validated approach to treating diseases at their genetic source by "interfering" with mRNA that cause or contribute to disease. Since our founding in 2002, Alnylam has led the RNAi Revolution and continues to turn scientific possibility into reality.

Our culture:Our people-first culture is guided by our core values: fiercely innovative, open culture, purposeful urgency, passion for excellence, and commitment to people, and these values influence how we work and the business decisions we make. Thanks to feedback from our employees over the years, we've been fortunate to be named a top employer around the world. Alnylam is extremely proud to have been recognized as one of Science Magazine's Top Biopharma Employers, one of America's Most Responsible Companies for 2024 by Newsweek, a Fast Company Best Workplace for Innovators, and a Great Place to Work in Canada, France, Italy, Spain, Switzerland, and UK - among others.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. We are dedicated to building an environment where employees can feel that they belong, can bring their authentic selves to work, and achieve to their full potential. By empowering employees to embrace their unique differences at work, our business grows stronger with advanced and original thinking, allowing us to bring groundbreaking medicines to patients.