Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 143 |
Sr. Manager, US Commercial Revenue
Cambridge, Massachusetts
Overview: Alnylam Pharmaceuticals is seeking a US TTR Revenue Senior Manager to join the US TTR Finance organization in one of Cambridge's most innovative, publicly traded biotech companies focused on translating the science of siRNA into h...
4h
| Job Type | Full Time |
Business Account Executive, TTR - Tacoma, WA
Cambridge, Massachusetts
Overview We are looking for experienced Business Account Executives (BAEs) with specialty sales experience to promote AMVUTTRA. hATTR patients often spend years undiagnosed and misdiagnosed. This is an amazing opportunity to educate and enh...
4h
| Job Type | Full Time |
Director, Financial Planning & Analysis, Business Development
Cambridge, Massachusetts
Overview: Alnylam Pharmaceuticals is seeking a Director of Business Development FP&A to serve as a senior, finance-focused partner within the Business Development Finance organization. This role is intended for a highly analytical, enterpri...
4h
| Job Type | Full Time |
Associate Director, Observational Data Methods and Analytics
Cambridge, Massachusetts
Overview: The Associate Director, Observational Methods and Analytics is focused on real-world and non-interventional methods and associated analysis to support execution of epidemiologic studies. Reporting to the Head of Epidemiology, the ...
10h
| Job Type | Full Time |
Associate Director, Customer Engagement Platforms
Cambridge, Massachusetts
Overview The Associate Director, Customer Engagement Platforms is responsible for hands-on execution, configuration, and day-to-day operational support of Alnylam's CRM ecosystem, with a primary focus on U.S. delivery and a clear eye toward...
10h
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The CTMS Administrator is responsible for performing the day-to-day operations and support of the Alnylam Clinical Trial Management System (CTMS) for the execution of clinical trials across the development portfolio. The individua...
10h
| Job Type | Full Time |
Business Account Executive, Rare Disease - Midwest (Indiana, Illinois)
Cambridge, Massachusetts
Overview We are looking for an experienced and talented Business Account Executive (BAE) to commercially represent GIVLAARIand OXLUMO in the United States and have a significant impact on the lives of AHP patients. AHP's represent a sub-gro...
10h
| Job Type | Full Time |
Director, Field Reimbursement Lead - West
Cambridge, Massachusetts
Overview: We are seeking a Director, Field Reimbursement Lead - East to manage a regional team of field reimbursement directors. The Field Reimbursement Team is a critical component of the commercial strategy and will work in close collabor...
1d
| Job Type | Full Time |
Associate Director, GxP Audits and Inspection Excellence
Cambridge, Massachusetts
Overview The Associate Director, GxP Audits and Inspection Excellence, serves as the lead for Alnylam's enterprise audit and inspection program, providing direction, governance, and oversight across all GxP domains. This role is responsible...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: The successful candidate will join an experienced team of toxicologists providing discovery and development support across a strong and diverse pipeline of programs spanning multiple disease areas. In addition to leading and contr...
1d
| Job Type | Full Time |