Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 1 - 10 of 105 |
Senior Director, Global Environmental Health, Safety and Sustainability
Cambridge, Massachusetts
Overview: The Senior Director, Global Environmental Health, Safety and Sustainability provides enterprise leadership for programs that protect employees, communities and the environment while enabling Alnylam's mission of transforming the l...
1d
| Job Type | Full Time |
Scientist, Biocatalysis & Protein Engineering
Cambridge, Massachusetts
Overview: The Scientist, Biocatalysis & Protein Engineering will discover, engineer, characterize, and optimize biocatalysts for oligonucleotide and small-molecule manufacturing processes. The successful candidate will develop and apply pro...
1d
| Job Type | Full Time |
Associate Medical Director, Global Safety Medical Review
Cambridge, Massachusetts
Overview Alnylam is the industry leader in the translation of RNA interference (RNAi) into a new class of innovative medicines with the potential to address the unmet needs of patients with debilitating diseases. Founded in 2002, Alnylam wa...
1d
| Job Type | Full Time |
Associate Director, Commercial Technology & Data Engineering
Cambridge, Massachusetts
Overview Alnylam is building an integrated commercial technology, data, and AI ecosystem to support customer engagement, patient services, analytics, and business growth. The Associate Director, Commercial Technology & Data Engineering serv...
1d
| Job Type | Full Time |
Senior Director, Global Pharmacovigilance Quality Assurance Lead
Philadelphia, Pennsylvania
Overview: The Senior Director, Global Pharmacovigilance Quality Assurance Lead provides executive leadership and independent quality oversight of Alnylam's global pharmacovigilance quality system. Reporting to the Vice President, R&D Qualit...
1d
| Job Type | Full Time |
Senior Director, Global Pharmacovigilance Quality Assurance Lead
Cambridge, Massachusetts
Overview: The Senior Director, Global Pharmacovigilance Quality Assurance Lead provides executive leadership and independent quality oversight of Alnylam's global pharmacovigilance quality system. Reporting to the Vice President, R&D Qualit...
1d
| Job Type | Full Time |
Senior Director, Global Pharmacovigilance Quality Assurance Lead
Overview: The Senior Director, Global Pharmacovigilance Quality Assurance Lead provides executive leadership and independent quality oversight of Alnylam's global pharmacovigilance quality system. Reporting to the Vice President, R&D Qualit...
1d
| Job Type | Full Time |
Associate Scientist II, Protein Sciences
Cambridge, Massachusetts
Overview We are seeking an associate scientist-II to join our protein sciences team to contribute to our protein production and conjugation efforts. The candidate must be independent, goal oriented, technically competent, and able to effici...
2d
| Job Type | Full Time |
Director, Digital HR Platforms
Cambridge, Massachusetts
Overview The Director, Digital HR Platforms is responsible for leading the strategy, governance, delivery, and optimization of Alnylam's core HR platform. This role will oversee Alnylam's enterprise Human Capital Management (HCM) system, Su...
4d
| Job Type | Full Time |
Director, Regulatory Technology
Cambridge, Massachusetts
Alnylam is the world's leading RNA interference (RNAi) company, dedicated to transforming the lives of patients through innovative medicines. As Alnylam continues to expand its global development and regulatory footprint, Regulatory Science...
6d
| Job Type | Full Time |