Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 11 - 20 of 75 |
Scientist, Research (Targeted Delivery)
Cambridge, Massachusetts
Overview The Research Department at Alnylam is seeking a Scientist to join a growing team responsible for advancing RNAi therapeutics into the future, by opening up targeted delivery to all tissues. The successful candidate will have a work...
15h
| Job Type | Full Time |
Manager, CMC Project Management
Cambridge, Massachusetts
Overview: The successful candidate will partner with CMC Technical Leads to manage multiple complex development projects to achieve product development and manufacturing goals. This role will collaborate with technical leads and internal st...
1d
| Job Type | Full Time |
Associate Legal Director, US Commercial
Cambridge, Massachusetts
Associate Director, Product Counsel Role Summary The Associate Director, Product Counsel will hold a pivotal position within the Commercial Legal Team, partnering with the US TTR marketing and sales teams to drive the success of the TTR fra...
1d
| Job Type | Full Time |
The Associate Director, Contract Manufacturing Pack and Label
Cambridge, Massachusetts
The Associate Director, Contract Manufacturing Pack and Label is a standalone role responsible for the strategic and operational management of contract manufacturers (CMOs) supporting commercial packaging and labeling operations within a de...
1d
| Job Type | Full Time |
Associate Director, Ethics and Compliance
Cambridge, Massachusetts
Associate Director, Global Investigations and Enterprise Risk Management, Ethics & Compliance Overview Reporting to the Head of Global Investigations & Enterprise Risk Management, the Associate Director, Ethics & Compliance, is responsible ...
1d
| Job Type | Full Time |
Senior Manager, Program Management
Cambridge, Massachusetts
Overview At Alnylam, clinical-stage development programs are managed by a Global Program Leadership Team, led by a Program Leader and a Program Manager, responsible for harnessing cross-functional expertise to define the best scientific, cl...
1d
| Job Type | Full Time |
Cambridge, Massachusetts
Senior Clinical Data Manager The Sr. CDM will lead and contribute to data management activities in support of Alnylam studies across all stages of clinical drug development. This position reports to the Director, Clinical Data Management. S...
2d
| Job Type | Full Time |
Senior Director, Audits, Inspections, & QMS
Cambridge, Massachusetts
Overview: Reporting to the SVP, Head of Quality Assurance & Quality Control, this is an enterprise leadership role and is responsible for providing strategic and operational leadership in the planning and execution of various elements acros...
2d
| Job Type | Full Time |
Manager, Patient Services Operations
Cambridge, Massachusetts
Overview The Manager, US Patient Services Operations role is a critical component of the Patient Services Operations team. Reporting to the Associate Director, US Patient Services Operations, within the Technology Enablement pillar, this ro...
2d
| Job Type | Full Time |
Senior Associate Scientist, Oncology Research - In Vivo
Cambridge, Massachusetts
Overview: The Oncology Research group at Alnylam is seeking a highly motivated Senior Associate Scientist to join our growing interdisciplinary team aimed at developing RNAi therapeutics against cancer. The successful candidate will have ha...
2d
| Job Type | Full Time |